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Validation of a 22-Gene Genomic Classifier in Patients With Recurrent Prostate Cancer: An Ancillary Study of the NRG/RTOG 9601 Randomized Clinical Trial

IMPORTANCE: Decipher (Decipher Biosciences Inc) is a genomic classifier (GC) developed to estimate the risk of distant metastasis (DM) after radical prostatectomy (RP) in patients with prostate cancer. OBJECTIVE: To validate the GC in the context of a randomized phase 3 trial. DESIGN, SETTING, AND P...

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Publicado en:JAMA Oncol
Autores principales: Feng, Felix Y., Huang, Huei-Chung, Spratt, Daniel E., Zhao, Shuang (George), Sandler, Howard M., Simko, Jeffry P., Davicioni, Elai, Nguyen, Paul L., Pollack, Alan, Efstathiou, Jason A., Dicker, Adam P., Todorovic, Tamara, Margrave, Jennifer, Liu, Yang (Seagle), Dabbas, Bashar, Thompson, Darby J. S., Das, Rajdeep, Dignam, James J., Sweeney, Christopher, Attard, Gerhardt, Bahary, Jean-Paul, Lukka, Himanshu R., Hall, William A., Pisansky, Thomas M., Shah, Amit B., Pugh, Stephanie L., Shipley, William U., Tran, Phuoc T.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Medical Association 2021
Materias:
Original Investigation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7879385/
https://ncbi.nlm.nih.gov/pubmed/33570548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2020.7671
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