Immunogenicity and crossreactivity of antibodies to the nucleocapsid protein of SARS-CoV-2: utility and limitations in seroprevalence and immunity studies

COVID-19 patients elicit strong responses to the nucleocapsid (N) protein of SARS-CoV-2 but binding antibodies are also detected in prepandemic individuals, indicating potential crossreactivity with common cold human coronaviruses (HCoV) and questioning its utility in seroprevalence studies. We inve...

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Publicado en:Transl Res
Main Authors: Dobaño, Carlota, Santano, Rebeca, Jiménez, Alfons, Vidal, Marta, Chi, Jordi, Rodrigo Melero, Natalia, Popovic, Matija, López-Aladid, Rubén, Fernández-Barat, Laia, Tortajada, Marta, Carmona-Torre, Francisco, Reina, Gabriel, Torres, Antoni, Mayor, Alfredo, Carolis, Carlo, García-Basteiro, Alberto L., Aguilar, Ruth, Moncunill, Gemma, Izquierdo, Luis
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier Inc. 2021
Assuntos:
Original Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7879156/
https://ncbi.nlm.nih.gov/pubmed/33582244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trsl.2021.02.006
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