Establishing a Case for Anti-complement Therapy in Membranous Nephropathy

INTRODUCTION: Membranous nephropathy (MN) is a common cause of adult nephrotic syndrome that progresses to end-stage kidney disease in up to 40% of cases. It is an autoimmune disease characterized by glomerular subepithelial deposits containing IgG. In experimental MN, these deposits activate comple...

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Bibliographic Details
Published in:Kidney Int Rep
Main Authors: Ayoub, Isabelle, Shapiro, John P., Song, Huijuan, Zhang, Xiaolan Lily, Parikh, Samir, Almaani, Salem, Madhavan, Sethu, Brodsky, Sergey V., Satoskar, Anjali, Bott, Cherri, Yu, Lianbo, Merchant, Michael, Klein, John, Mejia-Vilet, Juan M., Nadasdy, Tibor, Birmingham, Dan, Rovin, Brad H.
Format: Artigo
Language:Inglês
Published: Elsevier 2020
Subjects:
Translational Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7879111/
https://ncbi.nlm.nih.gov/pubmed/33615073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ekir.2020.11.032
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