Tryptophan Metabolism Regulates Proliferative Capacity of Human Pluripotent Stem Cells

Human pluripotent stem cells (hPSCs) have a unique metabolic signature for maintenance of pluripotency, self-renewal, and survival. Although hPSCs could be potentially used in regenerative medicine, the prohibitive cost associated with large-scale cell culture presents a major barrier to the clinica...

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Pubblicato in:iScience
Autori principali: Someya, Shota, Tohyama, Shugo, Kameda, Kotaro, Tanosaki, Sho, Morita, Yuika, Sasaki, Kazunori, Kang, Moon-Il, Kishino, Yoshikazu, Okada, Marina, Tani, Hidenori, Soma, Yusuke, Nakajima, Kazuaki, Umei, Tomohiko, Sekine, Otoya, Moriwaki, Taijun, Kanazawa, Hideaki, Kobayashi, Eiji, Fujita, Jun, Fukuda, Keiichi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7878994/
https://ncbi.nlm.nih.gov/pubmed/33615198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2021.102090
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