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Gastruloid Development Competence Discriminates Different States of Pluripotency
Floating spheroidal aggregates of mouse embryonic stem cells can develop into polarized/elongated organoids, namely gastruloids. We set up a high-performing assay to measure gastruloid formation efficiency (GFE), and found that GFE decreases as pluripotency progresses from naive (GFE ≥ 95%) to prime...
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| Publicado no: | Stem Cell Reports |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7878839/ https://ncbi.nlm.nih.gov/pubmed/33482102 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2020.12.013 |
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