Case Report: Fatal Multiorgan Failure and Heterochronous Pneumonitis Following Pembrolizumab Treatment in a Patient With Large-Cell Neuroendocrine Carcinoma of Lung

Immune checkpoint inhibitors have radically changed the landscape of antitumor therapies in several malignancies. Despite the long-term efficacy, severe immune-related adverse events (irAEs) were not uncommon. However, fatal simultaneous multiorgan failure was rare. Here, we described a patient who...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:Front Pharmacol
المؤلفون الرئيسيون: Xie, Xiaohong, Wang, Fei, Qin, Yinyin, Lin, Xinqing, Xie, Zhanhong, Liu, Ming, Ouyang, Ming, Luo, Bihui, Gu, Yingying, Li, Shiyue, Gu, Dejian, Chen, Rongrong, Zhou, Chengzhi
التنسيق: Artigo
اللغة:Inglês
منشور في: Frontiers Media S.A. 2021
الموضوعات:
Pharmacology
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC7878548/
https://ncbi.nlm.nih.gov/pubmed/33584255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.569466
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