Mapping of susceptible variants for cold medicine-related Stevens–Johnson syndrome by whole-genome resequencing

Stevens–Johnson syndrome (SJS) and its severe condition with extensive skin detachment and a poor prognosis, toxic epidermal necrolysis (TEN), are immunologically mediated severe cutaneous reactions of the skin and mucous membranes such as the ocular surface. Genetic variations on the HLA-A and othe...

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Enregistré dans:
Détails bibliographiques
Publié dans:NPJ Genom Med
Auteurs principaux: Kawai, Yosuke, Hitomi, Yuki, Ueta, Mayumi, Khor, Seik-Soon, Nakatani, Ken, Sotozono, Chie, Kinoshita, Shigeru, Nagasaki, Masao, Tokunaga, Katsushi
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2021
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7878485/
https://ncbi.nlm.nih.gov/pubmed/33574277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41525-021-00171-2
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