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Hormonal regulation of Semaphorin 7a in ER+ breast cancer drives therapeutic resistance

Approximately 70% of all breast cancers are estrogen receptor positive (ER+BC) and endocrine therapy has improved survival for patients with ER+BC. However, up to half of these tumors recur within 20 years. Recurrent ER+BCs develop resistance to endocrine therapy; thus, novel targets are needed to t...

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Bibliographische Detailangaben
Veröffentlicht in:Cancer Res
Hauptverfasser: Crump, Lyndsey S., Wyatt, Garhett L., Rutherford, Taylor R., Richer, Jennifer K., Porter, Weston W., Lyons, Traci R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7878309/
https://ncbi.nlm.nih.gov/pubmed/33122307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-20-1601
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