Epineural optogenetic activation of nociceptors initiates and amplifies inflammation

Activation of nociceptor sensory neurons by noxious stimuli both triggers pain and increases capillary permeability and blood flow to produce neurogenic inflammation(1,2), but whether nociceptors also interact with the immune system remains poorly understood. Here we report a neurotechnology for sel...

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Detalhes bibliográficos
Publicado no:Nat Biotechnol
Main Authors: Michoud, Frédéric, Seehus, Corey, Schönle, Philipp, Brun, Noé, Taub, Daniel, Zhang, Zihe, Jain, Aakanksha, Furfaro, Ivan, Akouissi, Outman, Moon, Rachel, Meier, Pascale, Galan, Katia, Doyle, Benjamin, Tetreault, Michael, Talbot, Sébastien, Browne, Liam E., Huang, Qiuting, Woolf, Clifford J., Lacour, Stéphanie P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7878280/
https://ncbi.nlm.nih.gov/pubmed/32958958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41587-020-0673-2
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