Anthocyanins from Hibiscus syriacus L. Inhibit NLRP3 Inflammasome in BV2 Microglia Cells by Alleviating NF-κB- and ER Stress-Induced Ca(2+) Accumulation and Mitochondrial ROS Production

Anthocyanins from the petals of Hibiscus syriacus L. (PS) possess anti-inflammatory, antioxidant, and antimelanogenic activities. However, it remains unclear whether PS inhibit the NLR family pyrin domain-containing 3 (NLRP3) inflammasome activation and assembly. This study is aimed at investigating...

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Publicado en:Oxid Med Cell Longev
Autores principales: Molagoda, Ilandarage Menu Neelaka, Lee, Kyoung Tae, Choi, Yung Hyun, Jayasingha, Jayasingha Arachchige Chathuranga Chanaka, Kim, Gi-Young
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi 2021
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7878077/
https://ncbi.nlm.nih.gov/pubmed/33613822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/1246491
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