Influence of neprilysin inhibition on the efficacy and safety of empagliflozin in patients with chronic heart failure and a reduced ejection fraction: the EMPEROR-Reduced trial

AIMS: We evaluated the influence of sacubitril/valsartan on the effects of sodium-glucose cotransporter 2 (SGLT2) inhibition with empagliflozin in patients with heart failure and a reduced ejection fraction. METHODS AND RESULTS: The EMPEROR-Reduced trial randomized 3730 patients with heart failure a...

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Veröffentlicht in:Eur Heart J
Hauptverfasser: Packer, Milton, Anker, Stefan D, Butler, Javed, Filippatos, Gerasimos, Ferreira, Joao Pedro, Pocock, Stuart J, Rocca, Hans-Peter Brunner-La, Janssens, Stefan, Tsutsui, Hiroyuki, Zhang, Jian, Brueckmann, Martina, Jamal, Waheed, Cotton, Daniel, Iwata, Tomoko, Schnee, Janet, Zannad, Faiez
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2021
Schlagworte:
Fast Track Clinical Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7878011/
https://ncbi.nlm.nih.gov/pubmed/33459776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehaa968
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