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Use of signals of positive and negative selection to distinguish cancer genes and passenger genes
A major goal of cancer genomics is to identify all genes that play critical roles in carcinogenesis. Most approaches focused on genes positively selected for mutations that drive carcinogenesis and neglected the role of negative selection. Some studies have actually concluded that negative selection...
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| Published in: | eLife |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
eLife Sciences Publications, Ltd
2021
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7877913/ https://ncbi.nlm.nih.gov/pubmed/33427197 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.59629 |
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