Cell-free DNA in spent culture medium effectively reflects the chromosomal status of embryos following culturing beyond implantation compared to trophectoderm biopsy

This prospective study evaluated the accuracy of non-invasive preimplantation genetic testing for aneuploidy (niPGT-A) using cell-free DNA in spent culture medium, as well as that of preimplantation genetic testing for aneuploidy (PGT-A) using trophectoderm (TE) biopsy after culturing beyond implant...

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Pubblicato in:PLoS One
Autori principali: Shitara, Akihiro, Takahashi, Kazumasa, Goto, Mayumi, Takahashi, Harunori, Iwasawa, Takuya, Onodera, Yohei, Makino, Kenichi, Miura, Hiroshi, Shirasawa, Hiromitsu, Sato, Wataru, Kumazawa, Yukiyo, Terada, Yukihiro
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2021
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7877764/
https://ncbi.nlm.nih.gov/pubmed/33571233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0246438
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