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A mixture model to detect edges in sparse co-expression graphs with an application for comparing breast cancer subtypes

We develop a method to recover a gene network’s structure from co-expression data, measured in terms of normalized Pearson’s correlation coefficients between gene pairs. We treat these co-expression measurements as weights in the complete graph in which nodes correspond to genes. To decide which edg...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Bar, Haim, Bang, Seojin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7877669/
https://ncbi.nlm.nih.gov/pubmed/33571253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0246945
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