Effects of L-DOPA on Gene Expression in the Frontal Cortex of Rats with Unilateral Lesions of Midbrain Dopaminergic Neurons

The development of Parkinson’s disease (PD) causes dysfunction of the frontal cortex, which contributes to the hallmark motor symptoms and is regarded as one of the primary causes of the affective and cognitive impairments observed in PD. Treatment with L-3,4-dihydroxyphenylalanine (L-DOPA) alleviat...

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Veröffentlicht in:eNeuro
Hauptverfasser: Radlicka, Anna, Kamińska, Kinga, Borczyk, Malgorzata, Piechota, Marcin, Korostyński, Michał, Pera, Joanna, Lorenc-Koci, Elżbieta, Rodriguez Parkitna, Jan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2021
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Research Article: New Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7877460/
https://ncbi.nlm.nih.gov/pubmed/33257528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0234-20.2020
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