Activity-Based Sensing with a Metal-Directed Acyl Imidazole Strategy Reveals Cell Type-Dependent Pools of Labile Brain Copper

Copper is a required nutrient for life and particularly important to the brain and central nervous system. Indeed, copper redox activity is essential to maintaining normal physiological responses spanning neural signaling to metabolism, but at the same time copper misregulation is associated with in...

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Bibliografiske detaljer
Udgivet i:J Am Chem Soc
Main Authors: Lee, Sumin, Chung, Clive Yik-Sham, Liu, Pei, Craciun, Laura, Nishikawa, Yuki, Bruemmer, Kevin J., Hamachi, Itaru, Saijo, Kaoru, Miller, Evan W., Chang, Christopher J.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7877313/
https://ncbi.nlm.nih.gov/pubmed/32815370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c05727
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