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A zebrafish model of granulin deficiency reveals essential roles in myeloid cell differentiation

Granulin is a pleiotropic protein involved in inflammation, wound healing, neurodegenerative disease, and tumorigenesis. These roles in human health have prompted research efforts to use granulin to treat rheumatoid arthritis and frontotemporal dementia and to enhance wound healing. But how granulin...

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Dettagli Bibliografici
Pubblicato in:Blood Adv
Autori principali: Campbell, Clyde A., Fursova, Oksana, Cheng, Xiaoyi, Snella, Elizabeth, McCune, Abbigail, Li, Liangdao, Solchenberger, Barbara, Schmid, Bettina, Sahoo, Debashis, Morton, Mark, Traver, David, Espín-Palazón, Raquel
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7876888/
https://ncbi.nlm.nih.gov/pubmed/33560393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020003096
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