The use of angiotensin-converting enzyme inhibitors vs. angiotensin receptor blockers and cognitive decline in Alzheimer’s disease: the importance of blood-brain barrier penetration and APOE ε4 carrier status

BACKGROUND: The antihypertensive angiotensin receptor blockers (ARBs) and angiotensin-converting enzyme inhibitors (ACE-Is) have similar indications and mechanisms of action, but prior work suggests divergence in their effects on cognition. METHODS: Participants in the National Alzheimer’s Coordinat...

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發表在:Alzheimers Res Ther
Main Authors: Ouk, Michael, Wu, Che-Yuan, Rabin, Jennifer S., Jackson, Aaron, Edwards, Jodi D., Ramirez, Joel, Masellis, Mario, Swartz, Richard H., Herrmann, Nathan, Lanctôt, Krista L., Black, Sandra E., Swardfager, Walter
格式: Artigo
語言:Inglês
出版: BioMed Central 2021
主題:
Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7876820/
https://ncbi.nlm.nih.gov/pubmed/33573702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-021-00778-8
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