Effect of Levothyroxine Therapy on the Development of Depressive Symptoms in Older Adults With Subclinical Hypothyroidism: An Ancillary Study of a Randomized Clinical Trial

IMPORTANCE: Previous trials on the effect of levothyroxine on depressive symptom scores in patients with subclinical hypothyroidism were limited by small sample sizes (N = 57 to 94) and potential biases. OBJECTIVE: To assess the effect of levothyroxine on the development of depressive symptoms in ol...

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Detalhes bibliográficos
Publicado no:JAMA Netw Open
Main Authors: Wildisen, Lea, Feller, Martin, Del Giovane, Cinzia, Moutzouri, Elisavet, Du Puy, Robert S., Mooijaart, Simon P., Collet, Tinh-Hai, Poortvliet, Rosalinde K. E., Kearney, Patricia, Quinn, Terence J., Klöppel, Stefan, Bauer, Douglas C., Peeters, Robin P., Westendorp, Rudi, Aujesky, Drahomir, Gussekloo, Jacobijn, Rodondi, Nicolas
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2021
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7876592/
https://ncbi.nlm.nih.gov/pubmed/33566107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamanetworkopen.2020.36645
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