Streptococcus pyogenes M1T1 Variants Induce an Inflammatory Neutrophil Phenotype Including Activation of Inflammatory Caspases

Invasive infections due to group A Streptococcus (GAS) advance rapidly causing tissue degradation and unregulated inflammation. Neutrophils are the primary immune cells that respond to GAS. The neutrophil response to GAS was characterised in response to two M1T1 isolates; 5448 and animal passaged va...

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Veröffentlicht in:Front Cell Infect Microbiol
Hauptverfasser: Williams, Jonathan G., Ly, Diane, Geraghty, Nicholas J., McArthur, Jason D., Vyas, Heema K. N., Gorman, Jody, Tsatsaronis, James A., Sluyter, Ronald, Sanderson-Smith, Martina L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Cellular and Infection Microbiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7876443/
https://ncbi.nlm.nih.gov/pubmed/33585270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2020.596023
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