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Mechanisms Governing Immunotherapy Resistance in Pancreatic Ductal Adenocarcinoma

Pancreatic ductal adenocarcinoma (PDA) is a lethal malignancy with an overall 5-year survival rate of 10%. Disease lethality is due to late diagnosis, early metastasis and resistance to therapy, including immunotherapy. PDA creates a robust fibroinflammatory tumor microenvironment that contributes t...

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Vydáno v:Front Immunol
Hlavní autoři: Schmiechen, Zoe C., Stromnes, Ingunn M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7876239/
https://ncbi.nlm.nih.gov/pubmed/33584701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.613815
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