Alternative splicing of ceramide synthase 2 alters levels of specific ceramides and modulates cancer cell proliferation and migration in Luminal B breast cancer subtype

Global dysregulation of RNA splicing and imbalanced sphingolipid metabolism has emerged as promoters of cancer cell transformation. Here, we present specific signature of alternative splicing (AS) events of sphingolipid genes for each breast cancer subtype from the TCGA-BRCA dataset. We show that ce...

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Publicado no:Cell Death Dis
Main Authors: Pani, Trishna, Rajput, Kajal, Kar, Animesh, Sharma, Harsh, Basak, Rituparna, Medatwal, Nihal, Saha, Sandhini, Dev, Gagan, Kumar, Sharwan, Gupta, Siddhi, Mukhopadhyay, Arnab, Malakar, Dipankar, Maiti, Tushar Kanti, Arimbasseri, Aneeshkumar G., Deo, S. V. S., Sharma, Ravi Datta, Bajaj, Avinash, Dasgupta, Ujjaini
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7876150/
https://ncbi.nlm.nih.gov/pubmed/33568634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03436-x
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