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Supraphysiological Levels of IL-2 in Jak3-Deficient Mice Promote Strong Proliferative Responses of Adoptively Transferred Naive CD8(+) T Cells
The antigen-independent, strong proliferative responses of naive CD8(+) T cells have been well demonstrated in a particular strain of mice lacking IL-2 receptors. This type of proliferation is mainly driven by common gamma-chain (γ(c)) cytokines, such as IL-2, IL-7, and IL-15, present at abnormally...
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| Publicado no: | Front Immunol |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7876067/ https://ncbi.nlm.nih.gov/pubmed/33584707 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.616898 |
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