Inhibition of miR-96-5p in the mouse brain increases glutathione levels by altering NOVA1 expression

Glutathione (GSH) is an important antioxidant that plays a critical role in neuroprotection. GSH depletion in neurons induces oxidative stress and thereby promotes neuronal damage, which in turn is regarded as a hallmark of the early stage of neurodegenerative diseases. The neuronal GSH level is mai...

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Publicat a:Commun Biol
Autors principals: Kinoshita, Chisato, Kikuchi-Utsumi, Kazue, Aoyama, Koji, Suzuki, Ryo, Okamoto, Yayoi, Matsumura, Nobuko, Omata, Daiki, Maruyama, Kazuo, Nakaki, Toshio
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7876013/
https://ncbi.nlm.nih.gov/pubmed/33568779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-01706-0
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