The HIF‐1α/p53/miRNA‐34a/Klotho axis in retinal pigment epithelial cells promotes subretinal fibrosis and exacerbates choroidal neovascularization

Wet age‐related macular degeneration (wAMD), characterized by choroidal neovascularization (CNV), is a leading cause of irreversible vision loss among elderly people in developed nations. Subretinal fibrosis, mediated by epithelial‐mesenchymal transition (EMT) of retinal pigment epithelium (RPE) cel...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Xie, Laiqing, Wang, Ying, Li, Quan, Ji, Xiaoyan, Tu, Yuanyuan, Du, Shu, Lou, Hui, Zeng, Xinwei, Zhu, Linling, Zhang, Ji, Zhu, Manhui
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7875902/
https://ncbi.nlm.nih.gov/pubmed/33438362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.16272
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados