AMPK signaling mediates synphilin-1-induced hyperphagia and obesity in Drosophila

Expression of synphilin-1 in neurons induces hyperphagia and obesity in a Drosophila model. However, the molecular pathways underlying synphilin-1-linked obesity remain unclear. Here, Drosophila models and genetic tools were used to study the synphilin-1-linked pathways in energy balance by combinin...

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Publicat a:J Cell Sci
Autors principals: Liu, Jingnan, Wang, Xiaobo, Ma, Rui, Li, Tianxia, Guo, Gongbo, Ning, Bo, Moran, Timothy H., Smith, Wanli W.
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists Ltd 2021
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7875497/
https://ncbi.nlm.nih.gov/pubmed/33443093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.247742
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