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BMP4 activates the Wnt–Lin28A–Blimp1–Wnt pathway to promote primordial germ cell formation via altering H3K4me2
The unique developmental characteristics of chicken primordial germ cells (PGCs) enable them to be used in recovery of endangered bird species, gene editing and the generation of transgenic birds, but the limited number of PGCs greatly limits their application. Studies have shown that the formation...
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| Veröffentlicht in: | J Cell Sci |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Company of Biologists Ltd
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7875490/ https://ncbi.nlm.nih.gov/pubmed/33443086 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.249375 |
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