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BMP4 activates the Wnt–Lin28A–Blimp1–Wnt pathway to promote primordial germ cell formation via altering H3K4me2

The unique developmental characteristics of chicken primordial germ cells (PGCs) enable them to be used in recovery of endangered bird species, gene editing and the generation of transgenic birds, but the limited number of PGCs greatly limits their application. Studies have shown that the formation...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Zuo, Qisheng, Jin, Kai, Wang, Man, Zhang, Yani, Chen, Guohong, Li, Bichun
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7875490/
https://ncbi.nlm.nih.gov/pubmed/33443086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.249375
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