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Identification and characterization of the enzymes responsible for the metabolism of the non-steroidal anti-inflammatory drugs, flunixin meglumine and phenylbutazone, in horses

The in vivo metabolism and pharmacokinetics of flunixin meglumine and phenylbutazone have been extensively characterized; however, there are no published reports describing the in vitro metabolism, specifically the enzymes responsible for the biotransformation of these compounds in horses. Due to th...

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Detalles Bibliográficos
Publicado en:J Vet Pharmacol Ther
Main Authors: Knych, Heather K., Finno, Carrie J., Baden, Russell, Arthur, Rick M., McKemie, Daniel S.
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7875478/
https://ncbi.nlm.nih.gov/pubmed/32757313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jvp.12891
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