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Retargeted and Stealth Modified Oncolytic Measles Viruses for Systemic Cancer Therapy in Measles-Immune Patients.

Measles viruses (MV) are rapidly inactivated by anti-measles neutralizing antibodies which has limited their clinical performance as oncolytic agents. Here, by substituting the H and F surface glycoproteins of MV with those from the homologous canine distemper virus (CDV) and engineering the CDV H a...

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Bibliografische gegevens
Gepubliceerd in:Mol Cancer Ther
Hoofdauteurs: Bah, Eugene S., Nace, Rebecca A., Peng, Kah Whye, Muñoz-Alía, Miguel Ángel, Russell, Stephen J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7875472/
https://ncbi.nlm.nih.gov/pubmed/32847970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-20-0134
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