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Pathways of calcium regulation, electron transport, and mitochondrial protein translation are molecular signatures of susceptibility to recurrent exertional rhabdomyolysis in Thoroughbred racehorses

Recurrent exertional rhabdomyolysis (RER) is a chronic muscle disorder of unknown etiology in racehorses. A potential role of intramuscular calcium (Ca(2+)) dysregulation in RER has led to the use of dantrolene to prevent episodes of rhabdomyolysis. We examined differentially expressed proteins (DEP...

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Pubblicato in:PLoS One
Autori principali: Aldrich, Kennedy, Velez-Irizarry, Deborah, Fenger, Clara, Schott, Melissa, Valberg, Stephanie J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7875397/
https://ncbi.nlm.nih.gov/pubmed/33566847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0244556
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