K18-hACE2 mice develop respiratory disease resembling severe COVID-19

SARS-CoV-2 emerged in late 2019 and resulted in the ongoing COVID-19 pandemic. Several animal models have been rapidly developed that recapitulate the asymptomatic to moderate disease spectrum. Now, there is a direct need for additional small animal models to study the pathogenesis of severe COVID-1...

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Bibliografski detalji
Izdano u:PLoS Pathog
Glavni autori: Yinda, Claude Kwe, Port, Julia R., Bushmaker, Trenton, Offei Owusu, Irene, Purushotham, Jyothi N., Avanzato, Victoria A., Fischer, Robert J., Schulz, Jonathan E., Holbrook, Myndi G., Hebner, Madison J., Rosenke, Rebecca, Thomas, Tina, Marzi, Andrea, Best, Sonja M., de Wit, Emmie, Shaia, Carl, van Doremalen, Neeltje, Munster, Vincent J.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2021
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7875348/
https://ncbi.nlm.nih.gov/pubmed/33465158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009195
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