Stereotypic neutralizing V(H) antibodies against SARS-CoV-2 spike protein receptor binding domain in patients with COVID-19 and healthy individuals

Stereotypic antibody clonotypes exist in healthy individuals and may provide protective immunity against viral infections by neutralization. We observed that 13 of 17 patients with COVID-19 had stereotypic variable heavy chain (V(H)) antibody clonotypes directed against the receptor binding domain (...

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Detalhes bibliográficos
Publicado no:Sci Transl Med
Main Authors: Kim, Sang Il, Noh, Jinsung, Kim, Sujeong, Choi, Younggeun, Yoo, Duck Kyun, Lee, Yonghee, Lee, Hyunho, Jung, Jongtak, Kang, Chang Kyung, Song, Kyoung-Ho, Choe, Pyoeng Gyun, Kim, Hong Bin, Kim, Eu Suk, Kim, Nam-Joong, Seong, Moon-Woo, Park, Wan Beom, Oh, Myoung-don, Kwon, Sunghoon, Chung, Junho
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2021
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7875332/
https://ncbi.nlm.nih.gov/pubmed/33397677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.abd6990
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