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PTEN Promoter Hypermethylation Is Associated with Breslow Thickness in Acral Melanoma on the Heel, Forefoot, and Hallux

BACKGROUND: Acral melanoma occurs on glabrous skin or the nail apparatus and is distinct from ultraviolet-related melanoma due to differing genetic alteration patterns. Although the pathogenesis of acral melanoma is not well understood, mechanical stress is thought to induce acral melanoma. The inci...

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Dettagli Bibliografici
Pubblicato in:Ann Dermatol
Autori principali: Park, Hae Seok, Kim, Jong Hoon, Cho, Mi Yeon, Chung, Kee Yang, Roh, Mi Ryung
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Korean Dermatological Association; The Korean Society for Investigative Dermatology 2021
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7875221/
https://ncbi.nlm.nih.gov/pubmed/33911808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5021/ad.2021.33.1.18
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