UHRF1 downregulation promotes T follicular helper cell differentiation by increasing BCL6 expression in SLE

BACKGROUND: Transcription factor B cell lymphoma 6 (BCL6) is a master regulator of T follicular helper (Tfh) cells, which play a crucial role in the pathogenesis of systemic lupus erythematosus (SLE). However, the mechanisms by which BCL6 expression is regulated are poorly understood. Ubiquitin-like...

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Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: Liu, Limin, Hu, Longyuan, Yang, Linxuan, Jia, Sujie, Du, Pei, Min, Xiaoli, Wu, Jiali, Wu, Haijing, Long, Hai, Lu, Qianjin, Zhao, Ming
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7874639/
https://ncbi.nlm.nih.gov/pubmed/33568199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-021-01007-7
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