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UHRF1 downregulation promotes T follicular helper cell differentiation by increasing BCL6 expression in SLE
BACKGROUND: Transcription factor B cell lymphoma 6 (BCL6) is a master regulator of T follicular helper (Tfh) cells, which play a crucial role in the pathogenesis of systemic lupus erythematosus (SLE). However, the mechanisms by which BCL6 expression is regulated are poorly understood. Ubiquitin-like...
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| 出版年: | Clin Epigenetics |
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| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2021
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7874639/ https://ncbi.nlm.nih.gov/pubmed/33568199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-021-01007-7 |
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