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The Amplex Red/horseradish peroxidase assay requires superoxide dismutase to measure hydrogen peroxide in the presence of NAD(P)H

A sensitive fluorescence assay based on Amplex Red (AR) oxidation by horseradish peroxidase (AR/HRP) is described which continuously monitor rates of H(2)O(2) production by microsomal enzymes in the presence of relatively high concentrations of NADPH. NADPH and NADH are known to interact with HRP an...

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Bibliographic Details
Published in:Free Radic Res
Main Authors: Mishin, Vladimir, Heck, Diane E, Laskin, Debra L, Laskin, Jeffrey D
Format: Artigo
Language:Inglês
Published: 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7874521/
https://ncbi.nlm.nih.gov/pubmed/32912004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10715762.2020.1821883
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