Translation of IRF-1 Restricts Hepatic Interleukin-7 Production to Types I and II Interferons: Implications for Hepatic Immunity

Interleukin-7 (IL-7) is an important cytokine with pivotal pro-survival functions in the adaptive immune system. However, the role of IL-7 in innate immunity is not fully understood. In the present study, the impact of hepatic IL-7 on innate immune cells was assessed by functional experiments as wel...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Rueschenbaum, Sabrina, Cai, Chengcong, Schmidt, Matthias, Schwarzkopf, Katharina, Dittmer, Ulf, Zeuzem, Stefan, Welsch, Christoph, Lange, Christian M.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2021
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7874116/
https://ncbi.nlm.nih.gov/pubmed/33584648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.581352
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