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Increased Expression of PPAR-γ Modulates Monocytes Into a M2-Like Phenotype in SLE Patients: An Implicative Protective Mechanism and Potential Therapeutic Strategy of Systemic Lupus Erythematosus

Systemic lupus erythematosus (SLE) is a spectrum of autoimmune disorders characterized by continuous inflammation and the production of autoantibodies. Monocytes, as precursors of dendritic cells and macrophages, are involved in the pathogenesis of SLE, particularly in the inflammatory reactions. Pr...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Liu, Yu, Luo, Shuangyan, Zhan, Yi, Wang, Jiayu, Zhao, Rui, Li, Yingjie, Zeng, Jinrong, Lu, Qianjin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7873911/
https://ncbi.nlm.nih.gov/pubmed/33584646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.579372
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