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How Well Can Multivariate and Univariate GWAS Distinguish Between True and Spurious Pleiotropy?

Quantification of the simultaneous contributions of loci to multiple traits, a phenomenon called pleiotropy, is facilitated by the increased availability of high-throughput genotypic and phenotypic data. To understand the prevalence and nature of pleiotropy, the ability of multivariate and univariat...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Fernandes, Samuel B., Zhang, Kevin S., Jamann, Tiffany M., Lipka, Alexander E.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7873880/
https://ncbi.nlm.nih.gov/pubmed/33584799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.602526
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