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Decoding Genetics of Congenital Heart Disease Using Patient-Derived Induced Pluripotent Stem Cells (iPSCs)

Congenital heart disease (CHD) is the most common cause of infant death associated with birth defects. Recent next-generation genome sequencing has uncovered novel genetic etiologies of CHD, from inherited and de novo variants to non-coding genetic variants. The next phase of understanding the genet...

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Publicat a:Front Cell Dev Biol
Autors principals: Lin, Hui, McBride, Kim L., Garg, Vidu, Zhao, Ming-Tao
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7873857/
https://ncbi.nlm.nih.gov/pubmed/33585486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.630069
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