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Fermentative Production of l-2-Hydroxyglutarate by Engineered Corynebacterium glutamicum via Pathway Extension of l-Lysine Biosynthesis

l-2-hydroxyglutarate (l-2HG) is a trifunctional building block and highly attractive for the chemical and pharmaceutical industries. The natural l-lysine biosynthesis pathway of the amino acid producer Corynebacterium glutamicum was extended for the fermentative production of l-2HG. Since l-2HG is n...

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Detalhes bibliográficos
Publicado no:Front Bioeng Biotechnol
Main Authors: Prell, Carina, Burgardt, Arthur, Meyer, Florian, Wendisch, Volker F.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7873477/
https://ncbi.nlm.nih.gov/pubmed/33585425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2020.630476
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