Gene networks and pathways for plasma lipid traits via multitissue multiomics systems analysis

Genome-wide association studies (GWASs) have implicated ∼380 genetic loci for plasma lipid regulation. However, these loci only explain 17–27% of the trait variance, and a comprehensive understanding of the molecular mechanisms has not been achieved. In this study, we utilized an integrative genomic...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Lipid Res
Main Authors: Blencowe, Montgomery, Ahn, In Sook, Saleem, Zara, Luk, Helen, Cely, Ingrid, Mäkinen, Ville-Petteri, Zhao, Yuqi, Yang, Xia
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2021
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7873371/
https://ncbi.nlm.nih.gov/pubmed/33561811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.RA120000713
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