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Gene networks and pathways for plasma lipid traits via multitissue multiomics systems analysis

Genome-wide association studies (GWASs) have implicated ∼380 genetic loci for plasma lipid regulation. However, these loci only explain 17–27% of the trait variance, and a comprehensive understanding of the molecular mechanisms has not been achieved. In this study, we utilized an integrative genomic...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Blencowe, Montgomery, Ahn, In Sook, Saleem, Zara, Luk, Helen, Cely, Ingrid, Mäkinen, Ville-Petteri, Zhao, Yuqi, Yang, Xia
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7873371/
https://ncbi.nlm.nih.gov/pubmed/33561811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.RA120000713
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