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Novel urinary glycan profiling by lectin array serves as the biomarkers for predicting renal prognosis in patients with IgA nephropathy

In IgA nephropathy (IgAN), IgA1 molecules are characterized by galactose deficiency in O-glycans. Here, we investigated the association between urinary glycosylation profile measured by 45 lectins at baseline and renal prognosis in 142 patients with IgAN. The primary outcome was estimated glomerular...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kawakita, Chieko, Mise, Koki, Onishi, Yasuhiro, Sugiyama, Hitoshi, Yoshida, Michihiro, Yamada, Masao, Wada, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7873239/
https://ncbi.nlm.nih.gov/pubmed/33564009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-77736-1
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