Induction of the IL-1RII decoy receptor by NFAT/FOXP3 blocks IL-1β-dependent response of Th17 cells

Derived from a common precursor cell, the balance between Th17 and Treg cells must be maintained within immune system to prevent autoimmune diseases. IL-1β-mediated IL-1 receptor (IL-1R) signaling is essential for Th17-cell biology. Fine-tuning of IL-1R signaling is controlled by two receptors, IL-1...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Kim, Dong Hyun, Kim, Hee Young, Cho, Sunjung, Yoo, Su-Jin, Kim, Won-Ju, Yeon, Hye Ran, Choi, Kyungho, Choi, Je-Min, Kang, Seong Wook, Lee, Won-Woo
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2021
Assuntos:
Immunology and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7872515/
https://ncbi.nlm.nih.gov/pubmed/33507149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.61841
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