Impact of the B.1.1.7 variant on neutralizing monoclonal antibodies recognizing diverse epitopes on SARS-CoV-2 Spike

The interaction of the SARS-CoV-2 Spike receptor binding domain (RBD) with the ACE2 receptor on host cells is essential for viral entry. RBD is the dominant target for neutralizing antibodies and several neutralizing epitopes on RBD have been molecularly characterized. Analysis of circulating SARS-C...

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Detalhes bibliográficos
Publicado no:bioRxiv
Main Authors: Graham, Carl, Seow, Jeffrey, Huettner, Isabella, Khan, Hataf, Kouphou, Neophytos, Acors, Sam, Winstone, Helena, Pickering, Suzanne, Galao, Rui Pedro, Lista, Maria Jose, Jimenez-Guardeno, Jose M, Laing, Adam G., Wu, Yin, Joseph, Magdalene, Muir, Luke, Ng, Weng M., Duyvesteyn, Helen M. E., Zhao, Yuguang, Bowden, Thomas A., Shankar-Hari, Manu, Rosa, Annachiara, Cherepanov, Peter, McCoy, Laura E., Hayday, Adrian C., Neil, Stuart J.D., Malim, Michael H., Doores, Katie J.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7872354/
https://ncbi.nlm.nih.gov/pubmed/33564766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.02.03.429355
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