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Collaboration between the Fab and Fc contribute to maximal protection against SARS-CoV-2 in nonhuman primates following NVX-CoV2373 subunit vaccine with Matrix-M(™) vaccination

Recently approved vaccines have already shown remarkable protection in limiting SARS-CoV-2 associated disease. However, immunologic mechanism(s) of protection, as well as how boosting alters immunity to wildtype and newly emerging strains, remain incompletely understood. Here we deeply profiled the...

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Detaylı Bibliyografya
Yayımlandı:bioRxiv
Asıl Yazarlar: Gorman, Matthew J, Patel, Nita, Guebre-Xabier, Mimi, Zhu, Alex, Atyeo, Caroline, Pullen, Krista M., Loos, Carolin, Goez-Gazi, Yenny, Carrion, Ricardo, Tian, Jing-Hui, Yaun, Dansu, Bowman, Kathryn, Zhou, Bin, Maciejewski, Sonia, McGrath, Marisa E., Logue, James, Frieman, Matthew B., Montefiori, David, Mann, Colin, Schendel, Sharon, Amanat, Fatima, Krammer, Florian, Saphire, Erica Ollmann, Lauffenburger, Douglas, Greene, Ann M., Portnoff, Alyse D., Massare, Michael J., Ellingsworth, Larry, Glenn, Gregory, Smith, Gale, Alter, Galit
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory 2021
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7872351/
https://ncbi.nlm.nih.gov/pubmed/33564763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.02.05.429759
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