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Modeling Bioavailable Concentrations in Zebrafish Cell Lines and Embryos Increases the Correlation of Toxicity Potencies across Test Systems

[Image: see text] Linking cellular toxicity to low-tier animal toxicity and beyond is crucial within the adverse outcome pathway concept and the 3R framework. This study aimed to determine and compare the bioavailable effect concentrations in zebrafish cell lines and embryos. Acute, short-term toxic...

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Detalhes bibliográficos
Publicado no:Environ Sci Technol
Main Authors: Lungu-Mitea, Sebastian, Vogs, Carolina, Carlsson, Gunnar, Montag, Maximiliane, Frieberg, Kim, Oskarsson, Agneta, Lundqvist, Johan
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2020
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7872314/
https://ncbi.nlm.nih.gov/pubmed/33320646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.est.0c04872
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