High genetic variability of Schmallenberg virus M-segment leads to efficient immune escape from neutralizing antibodies

Schmallenberg virus (SBV) is the cause of severe fetal malformations when immunologically naïve pregnant ruminants are infected. In those malformed fetuses, a “hot-spot”-region of high genetic variability within the N-terminal region of the viral envelope protein Gc has been observed previously, and...

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Sparad:
Bibliografiska uppgifter
I publikationen:PLoS Pathog
Huvudupphovsmän: Wernike, Kerstin, Reimann, Ilona, Banyard, Ashley C., Kraatz, Franziska, La Rocca, S. Anna, Hoffmann, Bernd, McGowan, Sarah, Hechinger, Silke, Choudhury, Bhudipa, Aebischer, Andrea, Steinbach, Falko, Beer, Martin
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2021
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7872300/
https://ncbi.nlm.nih.gov/pubmed/33497419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009247
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