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Bisphenol-C is the strongest bifunctional ERα-agonist and ERβ-antagonist due to magnified halogen bonding

We reported that bisphenol AF (BPAF) works as an agonist for estrogen receptor (ER) ERα but as an antagonist for ERβ. Similar results were observed for bisphenol E analogs (BPE-X) such as BPE-F, BPE-Cl, and BPE-Br, each consisting of a series of a tri-halogenated methyl group CX(3) in the central al...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Liu, Xiaohui, Suyama, Keitaro, Nose, Takeru, Shimohigashi, Miki, Shimohigashi, Yasuyuki
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7872235/
https://ncbi.nlm.nih.gov/pubmed/33561155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0246583
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