A stratified phase I dose escalation trial of hypofractionated radiotherapy followed by ipilimumab in metastatic melanoma: long-term follow-up and final outcomes

We conducted a phase I dose-escalation trial of radiation with ipilimumab in patients with melanoma with ≥2 metastatic lesions. Here, we report the final full clinical analysis. Patients received RT (6 or 8 Gy x 2 or 3 doses) to a single lesion followed by 4 cycles of ipilimumab. The primary endpoin...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Maity, Amit, Mick, Rosemarie, Rengan, Ramesh, Mitchell, Tara C., Amaravadi, Ravi K., Schuchter, Lynn M., Pryma, Daniel A., Patsch, Dana M., Maity, Alisha P., Minn, Andy J., Vonderheide, Robert H., Lukens, John N.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2021
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7872096/
https://ncbi.nlm.nih.gov/pubmed/33643689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2020.1863631
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