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Cytotoxicity effect of trastuzumab on canine peripheral blood mononuclear cells

BACKGROUND: Trastuzumab is an antibody drug used to treat human epidermal growth factor receptor 2 (HER2) overexpressing human metastatic breast cancer. Antibody-dependent cellular cytotoxicity (ADCC) is considered to be the major mechanism of cytotoxicity of the drug. However, its ability to induce...

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Pubblicato in:Iran J Vet Res
Autori principali: Oyamada, T., Okano, S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: School of Veterinary Medicine, University of Shiraz 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7871734/
https://ncbi.nlm.nih.gov/pubmed/33584838
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